PTSD nightmares: practical outpatient options

Start with education and sleep basics. Add meds if needed.
First‑line medicine is prazosin. Titrate slow, watch BP.
Teach Imagery Rehearsal Therapy (IRT). It works and is brief.

Quick start

  • Explain nightmares in PTSD. Normalize and set a simple plan.

  • Sleep basics: fixed wake time, no alcohol near bed, limit late caffeine, wind‑down routine, dark/cool room.

Med options (adult outpatient)

  • Prazosin at bedtime. Start 1 mg qHS. Increase by 1 mg every few nights as tolerated (often 2–6 mg total; sometimes higher). Watch dizziness/orthostasis, check BP.

  • If prazosin not tolerated/ineffective, consider:

    • Clonidine or guanfacine for hyperarousal/sleep onset

    • Low‑dose trazodone or doxepin for insomnia features

    • Mirtazapine when depression/anxiety + poor appetite/weight loss

  • Check for OSA, pain, substance use, or meds that worsen sleep.

IRT in 5 minutes

  • Pick one frequent nightmare. Rewrite it with a safe/neutral ending.

  • Rehearse the new version while awake 5–10 minutes daily.

  • Practice for 2–4 weeks. Track frequency and distress.

Follow‑up plan

  • Recheck weekly during titration. Ask: time to fall asleep, awakenings, nightmare count, daytime function.

  • If better: hold dose and extend visit interval. If not: adjust dose or switch plan.

When to escalate

  • Syncope or severe orthostasis

  • High suicide risk or severe depression

  • Suspected OSA (snoring, pauses, daytime sleepiness) → sleep study referral

Want an IRT handout + prazosin titration card? I can add printable PDFs and smart phrases.

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ADHD MD Workflow: safety, handoffs, and fewer last‑minute refills